7. Antiviral Agents Induced Nephrotoxicity and Tubular Damage
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چکیده
منابع مشابه
Hydrogen sulfide ameliorates the kidney dysfunction and damage in cisplatin-induced nephrotoxicity in rat
Hydrogen Sulfide (H2S) prevents and treats a variety of disorders via its cytoprotective effects. However, the effects of H2S on rats with cisplatin (CP) nephrotoxicity are unclear. The aim was to study the effects of H2S on rats with CP nephrotoxicity. Thirty male Sprague-Dawley rats were divided into three groups: control group, nephrotoxic group received sing...
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Cisplatin (CSP) is a chemotherapeutic agent commonly used to treat a variety of malignancies. The major setback with CSP treatment is that its clinical efficacy is compromised by its induction of organ toxicity, particular to the kidneys and ears. Despite the significant strides that have been made in understanding the mechanisms underlying CSP-induced renal toxicity, advances in developing ren...
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*Corresponding author: Sandra Rodríguez Salgueiro, Electron Microscopy Laboratory, National Center for Scientific Research, Cubanacán, Havana, Cuba. E-mail: [email protected] Aminoglycosides are a family of antibiotics widely used in clinical practice. Their prescription is restricted by cytotoxicity and accumulation of antibiotic in renal tissues (1). Although renal damage induced b...
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A vaccine is a biological preparation that improves immunity to a particular disease. A vac‐ cine typically contains an agent that resembles a disease-causing microorganism, and is of‐ ten made from weakened or killed forms of the microbe, its toxins or one of its surface proteins. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and "remember" it, so...
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A major area in cancer therapy is the search for protective strategies against cisplatin-induced nephrotoxicity. We investigated the protective effect of cilastatin on cisplatin-induced injury to renal proximal tubular cells. Cilastatin is a specific inhibitor of renal dehydrodipeptidase I (DHP-I), which prevents hydrolysis of imipenem and its accumulation in the proximal tubule. Primary cultur...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2018
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.107.878